20 results

"I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis.

Journal Article
Welsh, P., & Brown, S. (2013)
"I'm not insane, my mother had me tested." The risks and benefits of being labelled 'at-risk' for psychosis. Health, Risk and Society, 15, 648-662. https://doi.org/10.1080/13698575.2013.848846
In this article we examine the identification of young people deemed to be at an elevated risk of developing psychosis (often referred to as an At-Risk Mental State for psycho...

Power and research: a qualitative approach to understanding the relationship between major mental illness, masculinity and violence

Digital Artefact
Haddow, C. (2018)
Power and research: a qualitative approach to understanding the relationship between major mental illness, masculinity and violence. [Sage Research Methods Case Study]
This case study reflects on research which explored the relationship between major mental illness and masculinity in the context of violent offending behavior. Studies which e...

Developing guidance to inform a clinically meaningful and feasible suicide risk assessment measure for use in emergency departments

Thesis
McClatchey, K. Developing guidance to inform a clinically meaningful and feasible suicide risk assessment measure for use in emergency departments. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/Output/1256366
Introduction: Over 800,000 people die by suicide each year, and despite being a global public health issue, limited research exists exploring suicide risk assessment practices...

Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety

Journal Article
Morgenroth, E., Orlov, N., Lythgoe, D. J., Stone, J. M., Barker, H., Munro, J., …Allen, P. (2019)
Altered relationship between prefrontal glutamate and activation during cognitive control in people with high trait anxiety. Cortex, 117, 53-63. https://doi.org/10.1016/j.cortex.2019.02.021
Trait anxiety can affect cognitive control resulting in ineffective and/or inefficient task performance. Moreover, previous functional Magnetic Resonance Imaging (fMRI) studie...

Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development.

Journal Article
Girardi, G., Fraser, J. A., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015)
Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. Molecular Psychiatry, 20, 1017-1026. https://doi.org/10.1038/mp.2014.110
In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of complement activation in placenta and foetal brain in vivo in u...

Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease

Journal Article
Hye, A., Kerr, F., Archer, N., Foy, C., Poppe, M., Brown, R., …Lovestone, S. (2004)
Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters, 373(1), 1-4. https://doi.org/10.1016/j.neulet.2004.10.031
Alzheimer's disease (AD) is a disorder without a molecular marker in peripheral tissues or a disease modifying treatment. As increasing evidence has suggested a role for glyco...

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

Journal Article
Kerr, F., Augustin, H., Piper, M. D. W., Gandy, C., Allen, M. J., Lovestone, S., & Partridge, L. (2011)
Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging, 32(11), 1977-1989. https://doi.org/10.1016/j.neurobiolaging.2009.10.015
Dietary restriction (DR) extends lifespan in diverse organisms and, in animal and cellular models, can delay a range of aging-related diseases including Alzheimer's disease (A...

A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia.

Thesis
Crerar, M. A. A computer-based microworld for the assessment and remediation of sentence processing deficits in aphasia. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/4968
This thesis investigates impairments of written sentence comprehension in 14 aphasic adults. The primary purpose of the research was to apply computer technology to the proces...

Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review

Journal Article
Graham, S. M., Baird, M., & Boyd, G. W. (2014)
Creatine supplementation and exercise as possible therapeutic treatments in Parkinson’s Disease: A review. Archives of Exercise in Health and Disease, 4(3), 286-298. https://doi.org/10.5628/aehd.v4i3.169
Parkinson’s disease (PD) is the second most common progressive neurodegenerative condition after Alzheimer’s Disease. It is characterized by a progressive loss of dopaminergic...

A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial

Journal Article
Pomeroy, V. M., Rowe, P., Clark, A., Walker, A., Kerr, A., Chandler, E., …Ugboule, U. C. (2016)
A Randomized Controlled Evaluation of the Efficacy of an Ankle-Foot Cast on Walking Recovery Early After Stroke: SWIFT Cast Trial. Neurorehabilitation and Neural Repair, 30(1), 40-48. doi:10.1177/1545968315583724
Background. Timely provision of an ankle-foot orthosis (AFO) orthotist customized for individuals early after stroke can be problematic. Objective. To evaluate the efficacy of...