Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages.
Journal Article
Barlow, P. G., Clouter-Baker, A., Donaldson, K., MacCallum, J., & Stone, V. (2005)
Carbon black nanoparticles induce type II epithelial cells to release chemotaxins for alveolar macrophages. Particle and fibre toxicology, 2(1), 11-24. https://doi.org/10.1186/1743-8977-2-11
Background - Alveolar macrophages are a key cell in dealing with particles deposited in the lungs and in determining the subsequent response to that particle exposure. Nanopar...
Antiinflammatory Steroid Action in Human Ovarian Surface Epithelial Cells
Journal Article
Hillier, S. G., Rae, M. T., Niven, D., Critchley, H. O. D., & Harlow, C. R. (2004)
Antiinflammatory Steroid Action in Human Ovarian Surface Epithelial Cells. Journal of Clinical Endocrinology and Metabolism, 89(9), 4538-4544. https://doi.org/10.1210/jc.2003-032225
The human ovarian surface epithelium (OSE) is subject to
serial injury and repair during ovulation, which is a natural inflammatory event. We asked whether there is a compensa...
Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents.
Journal Article
Dias, N., Goossens, J., Baldeyrou, B., Lansiaux, A., Colson, P., Di Salvo, A., …Bailly, C. (2005)
Oxoazabenzo[de]anthracenes conjugated to Amino Acids: Synthesis and evaluation as DNA-binding antitumor agents. Bioconjugate Chemistry, 16(4), 949-958. https://doi.org/10.1021/bc050065x
We report the synthesis of an original series of oxoazabenzo[de]anthracenes conjugated to an amino acid: Ala, Phe, Pro, Lys, or Gly (4a-e, respectively). The compounds, derive...
Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure
Journal Article
Ramage, L., & Guy, K. (2004)
Expression of C-Reactive Protein and Heat-Shock Protein-70 in the Lung Epithelial Cell Line A549, in Response to PM10 Exposure. Inhalation Toxicology, 16(6-7), 447-452. https://doi.org/10.1080/08958370490439614
Increased levels of C-reactive protein (CRP) and heat-shock protein-70 (Hsp70) in plasma are known to be associated with an increased risk of cardiovascular disease. In this s...
Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats
Journal Article
McQueen, D. S., Bond, S. M., Smith, P. J., Balali-Mood, K., & Smart, D. (2004)
Cannabidiol lacks the vanilloid VR1-mediated vasorespiratory effects of capsaicin and anandamide in anaesthetised rats. European Journal of Pharmacology, 491(2-3), 181-189. https://doi.org/10.1016/j.ejphar.2004.03.045
The results of vasorespiratory studies in rats anaesthetised with pentobarbital show that (±) cannabidiol, a cannabinoid that lacks psychotropic actions and is inactive at can...
Inhibition of lipopolysaccharide-induced inflammation by nippostrongylus brasiliensis larvae and excretory-secretory products (es)
Thesis
Zhao, M. Inhibition of lipopolysaccharide-induced inflammation by nippostrongylus brasiliensis larvae and excretory-secretory products (es)
(Thesis). Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/2549
Nippostrongylus brasiliensis is a rodent intestinal nematode with an important pulmonary migrating stage. Previous studies have observed a lack of TNF-α production and minimal...
Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571.
Journal Article
Jørgensen, H. G., Elliott, M. A., Allan, E. K., Carr, C. E., Holyoake, T. L. & Smith, K. (2002)
Alpha-1-acid glycoprotein expressed in the plasma of chronic myeloid leukemia patients does not mediate significant in vitro resistance to STI571. Blood. 99, 713-715. doi:10.1182/blood.V99.2.713. ISSN 0006-4971
Despite the efficacy of STI571 (Glivec, Novartis, Basle, Switzerland) in treating chronic myeloid leukemia (CML), drug resistance has already been noted both in vitro and in v...
Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression and NF-kB activation.
Journal Article
Duffin, R., Gilmour, P. S., Schins, R. P. F., Clouter, A., Guy, K., Brown, D. M., …Stone, V. (2001)
Aluminium lactate treatment of DQ12 quartz inhibits its ability to cause inflammation, chemokine expression and NF-kB activation. Toxicology and Applied Pharmacology. 176, 10-17. doi:10.1006/taap.2001.9268. ISSN 0041-008X
In 1997, an IARC Working Group classified quartz (crystalline silica) as a Group 1 lung carcinogen, but only in some industries, i.e., the quartz hazard is a variable entity. ...