cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival
Journal Article
Gubbay, O., Rae, M. T., McNeilly, A. S., Donadeu, F. X., Zeleznik, A. J., & Hillier, S. G. (2006)
cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival. Journal of Endocrinology, 191(1), 275-285. https://doi.org/10.1677/joe.1.06928
cAMP response-element binding (CREB) transcription factors transduce cell survival responses to peptide hormones and growth factors in normal tissues and mutant CREB proteins ...
Does hysterectomy in a premenopausal woman affect ovarian function?
Journal Article
Chalmers, C. (1996)
Does hysterectomy in a premenopausal woman affect ovarian function?. Medical Hypotheses, 46(6), 573-575. https://doi.org/10.1016/S0306-9877%2896%2990134-6
Women undergoing a hysterectomy without oophorectomy in their premenopausal years would expect to benefit from continued secretion of oestrogens to protect them from the condi...
Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome
Thesis
Ramaswamy, S. Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/9826
Polycystic Ovary Syndrome (PCOS) is a complex disorder encompassing reproductive and metabolic dysfunction. Ovarian hyperandrogenism is an endocrine hallmark of human PCOS. In...
Programming of adult cardiovascular function after early maternal undernutrition in sheep
Journal Article
Gopalakrishnan, G. S., Gardner, D. S., Rhind, S. M., Rae, M. T., Kyle, C. E., Brooks, A. N., …Symonds, M. E. (2004)
Programming of adult cardiovascular function after early maternal undernutrition in sheep. American journal of physiology: regulatory, integrative and comparative physiology, 287(1), R12-R20. https://doi.org/10.1152/ajpregu.00687.2003
The prenatal nutritional environment influences the subsequent risk of hypertension in adulthood. Animal studies have used, generally, the rat as a model species to illustrate...
Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney
Journal Article
Brennan, K. A., Gopalakrishnan, G. S., Kurlak, L., Rhind, S. M., Kyle, C. E., Brooks, A. N., …Symonds, M. E. (2005)
Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney. Reproduction, 129, 151-159. https://doi.org/10.1530/rep.1.00229
Epidemiological and animal studies strongly indicate that the environment experienced in utero determines, in part, an individual’s likelihood of developing cardiovascular dis...
Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis.
Journal Article
Rae, M. T., Niven, D., Ross, A., Forster, T., Lathe, R., Critchley, H. O. D., …Hillier, S. G. (2004)
Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis. Journal of Endocrinology, 183, 19-28. https://doi.org/10.1677/joe.1.05754
The human ovarian surface epithelium (HOSE) is a common site of gynaecological disease including endometriosis and ovarian cancer, probably due to serial injury-repair events ...
In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis.
Journal Article
Kanellopoulos-Langevin, C., Connolly, F., Rae, M. T., Späth, K., Boswell, L., McNeilly, A. S., & Duncan, W. C. (2015)
In an ovine model of polycystic ovary syndrome (PCOS) prenatal androgens suppress female fetal renal gluconeogenesis. PLOS ONE, 10, https://doi.org/10.1371/journal.pone.0132113
Increased maternal androgen exposure during pregnancy programmes a polycystic ovary syndrome (PCOS)-like condition, with metabolic dysfunction, in adult female offspring. Othe...
Cancer survivors' exercise barriers, facilitators and preferences in the context of fatigue, quality of life and physical activity participation: a questionnaire-survey: Cancer survivors' exercise barriers
Journal Article
Blaney, J. M., Lowe-Strong, A., Rankin-Watt, J., Campbell, A., & Gracey, J. H. (2013)
Cancer survivors' exercise barriers, facilitators and preferences in the context of fatigue, quality of life and physical activity participation: a questionnaire-survey: Cancer survivors' exercise barriers. Psycho-Oncology, 22(1), 186-194. https://doi.org/10.1002/pon.2072
ObjectiveTo investigate the exercise barriers, facilitators and preferences of a mixed sample of cancer survivors as well as fatigue levels, quality of life (QoL) and the freq...
Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development.
Journal Article
Girardi, G., Fraser, J. A., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015)
Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. Molecular Psychiatry, 20, 1017-1026. https://doi.org/10.1038/mp.2014.110
In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of
complement activation in placenta and foetal brain in vivo in u...
A focus group study exploring gynecological cancer survivors’ experiences and perceptions of participating in a RCT testing the efficacy of a home-based physical activity intervention
Journal Article
Donnelly, C. M., Lowe-Strong, A., Rankin, J. P., Campbell, A., Blaney, J. M., & Gracey, J. H. (2013)
A focus group study exploring gynecological cancer survivors’ experiences and perceptions of participating in a RCT testing the efficacy of a home-based physical activity intervention. Supportive Care in Cancer, 21(6), 1697-1708. https://doi.org/10.1007/s00520-012-1716-0
This study aims to explore gynecological cancer survivors' perceptions and experiences following participation in a randomised controlled trial (RCT) testing the efficacy of a...