35 results

Benefits of a worksite or home-based bench stepping intervention for sedentary middle-aged adults - a pilot study

Journal Article
Mair, J. L., Boreham, C. A., Ditroilo, M., McKeown, D., M. Lowery, M., Caulfield, B., & De Vito, G. (2014)
Benefits of a worksite or home-based bench stepping intervention for sedentary middle-aged adults - a pilot study. Clinical Physiology and Functional Imaging, 34(1), 10-17. https://doi.org/10.1111/cpf.12056
The aim of this study was to investigate the benefits of a low-volume, vigorous intensity bench stepping programme in sedentary middle-aged adults. Thirty-one healthy but sede...

cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival

Journal Article
Gubbay, O., Rae, M. T., McNeilly, A. S., Donadeu, F. X., Zeleznik, A. J., & Hillier, S. G. (2006)
cAMP response element-binding (CREB) signalling and ovarian surface epithelial cell survival. Journal of Endocrinology, 191(1), 275-285. https://doi.org/10.1677/joe.1.06928
cAMP response-element binding (CREB) transcription factors transduce cell survival responses to peptide hormones and growth factors in normal tissues and mutant CREB proteins ...

Does hysterectomy in a premenopausal woman affect ovarian function?

Journal Article
Chalmers, C. (1996)
Does hysterectomy in a premenopausal woman affect ovarian function?. Medical Hypotheses, 46(6), 573-575. https://doi.org/10.1016/S0306-9877%2896%2990134-6
Women undergoing a hysterectomy without oophorectomy in their premenopausal years would expect to benefit from continued secretion of oestrogens to protect them from the condi...

Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome

Thesis
Ramaswamy, S. Pancreatic and adrenal development and function in an ovine model of polycystic ovary syndrome. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/9826
Polycystic Ovary Syndrome (PCOS) is a complex disorder encompassing reproductive and metabolic dysfunction. Ovarian hyperandrogenism is an endocrine hallmark of human PCOS. In...

Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship

Journal Article
Christensen, J. F., Bandak, M., Campbell, A., Jones, L. W., & Højman, P. (2015)
Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta oncologica, 54(5), 592-599. https://doi.org/10.3109/0284186x.2014.995776
Treatment of testicular germ cell cancer constitutes a major success story in modern oncology. Today, the vast majority of patients are cured by a therapeutic strategy using o...

Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells

Journal Article
Sakka, E., Rae, M., Bramley, T., & Aitken, J. (1997)
Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells. Biology of Reproduction, 57(2), 428-435
We measured the production of reactive oxygen species (ROS) using luminol-horseradish peroxidase-induced chemiluminescence in mechanically dispersed cell suspensions from bovi...

Ovulation and Ovarian Cancer

Book Chapter
Hillier, S. G., Rae, M. T., & Gubbay, O. (2008)
Ovulation and Ovarian Cancer. In Hormonal Carcinogenesis V; (171-178). Springer. https://doi.org/10.1007/978-0-387-69080-3_16
Ovarian cancer (OC) most frequently arises from the ovarian surface epithelium (OSE), which comprises a single layer of mesothelial, squamous-to-cuboidal cells covering the en...

Programming of adult cardiovascular function after early maternal undernutrition in sheep

Journal Article
Gopalakrishnan, G. S., Gardner, D. S., Rhind, S. M., Rae, M. T., Kyle, C. E., Brooks, A. N., …Symonds, M. E. (2004)
Programming of adult cardiovascular function after early maternal undernutrition in sheep. American journal of physiology: regulatory, integrative and comparative physiology, 287(1), R12-R20. https://doi.org/10.1152/ajpregu.00687.2003
The prenatal nutritional environment influences the subsequent risk of hypertension in adulthood. Animal studies have used, generally, the rat as a model species to illustrate...

Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney

Journal Article
Brennan, K. A., Gopalakrishnan, G. S., Kurlak, L., Rhind, S. M., Kyle, C. E., Brooks, A. N., …Symonds, M. E. (2005)
Impact of maternal undernutrition and fetal number on glucocorticoid, growth hormone and insulin-like growth factor receptor mRNA abundance in the ovine fetal kidney. Reproduction, 129, 151-159. https://doi.org/10.1530/rep.1.00229
Epidemiological and animal studies strongly indicate that the environment experienced in utero determines, in part, an individual’s likelihood of developing cardiovascular dis...

Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis.

Journal Article
Rae, M. T., Niven, D., Ross, A., Forster, T., Lathe, R., Critchley, H. O. D., …Hillier, S. G. (2004)
Steroid signalling in human ovarian surface epithelial cells: the response to interleukin-1alpha determined by microarray analysis. Journal of Endocrinology, 183, 19-28. https://doi.org/10.1677/joe.1.05754
The human ovarian surface epithelium (HOSE) is a common site of gynaecological disease including endometriosis and ovarian cancer, probably due to serial injury-repair events ...