Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
Journal Article
Sandilands, E., Serrels, B., McEwan, D. G., Morton, J. P., Macagno, J. P., McLeod, K., …Frame, M. C. (2012)
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling. Nature Cell Biology, 14(1), 51-60. https://doi.org/10.1038/ncb2386
Here we describe a mechanism that cancer cells use to survive when flux through the Src/FAK pathway is severely perturbed. Depletion of FAK, detachment of FAK-proficient cells...
Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks
Journal Article
Lowrie, A. G., Dickinson, P., Wheelhouse, N., Stewart, G. D., Ross, A. J., Forster, T., & Ross, J. A. (2011)
Proteolysis-inducing factor core peptide mediates dermcidin-induced proliferation of hepatic cells through multiple signalling networks. International Journal of Oncology, 39(3), 709-18. https://doi.org/10.3892/ijo.2011.1064
Dermcidin is a candidate oncogene capable of increasing the number of cultured neuronal, breast cancer and prostate cancer cells and improving the survival of hepatic c...
Thyroid hormone signaling in human ovarian surface epithelial cells.
Journal Article
Rae, M. T., Gubbay, O., NaKostogiannou, A., Price, D., Critchley, H. O. D. & Hillier, S. G. (2007)
Thyroid hormone signaling in human ovarian surface epithelial cells. Journal of Clinical Endocrinology and Metabolism. 92, 322-327. doi:10.1210/jc.2006-1522. ISSN 0021-972X
Ovarian surface epithelial (OSE) cells express multiple nuclear hormone receptor genes, including those encoding thyroid hormone and estrogen receptors (TR and ER, respectivel...