Gary Hutchison
Gary Hutchison

Prof Gary Hutchison BSc MSc PhD

Dean of Applied Sciences

Biography

Professor Gary Hutchison was appointed Dean of School in August 2015.

Prof. Hutchison undertook his scientific training by completing an Honours degree in Molecular and Cell Biology at the University of Stirling and went on to study an MSc in Drug Design and Biomedical Science before undertaking a PhD examining the toxicology of inhaled particles at Napier University. In 2004 he began his post-doctoral career with the Medical Research Council in the Human Reproductive Sciences Unit, where he held two posts.

Prof. Hutchison is Dean of School of Applied Sciences with responsibility for Life Sciences, Social Sciences, Psychology, Teacher Education and Sport, Exercise and Health Sciences. In addition to leading the School, Prof. Hutchison is a member of the University Senior Leadership Team, Lead for the Borderlands Region and City Deal Mountain Bike Innovation Centre project, and Chair of the University Environmental Sustainability Strategy Group.

Prof. Hutchison has been an independent scientific advisor to the UK Government for more than 10 years and currently holds membership of FSA Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment; Defra’s College of Scientific Experts; and is a member of the FSA and Office for Product Safety & Standards registers of specialists. Previous memberships include Defra’s Hazardous Substances Advisory Committee (HSAC), the NANoREG UK steering group, and UK Government Nanotechnologies Strategy Forum.

Prof. Hutchison contributes to leadership across the sector by Chairing the Scottish Institute for Policing Research Board of Governance and is Chair of the Edinburgh Exchange Initiative, and membership of the MASTS Governing Council. He is an active member of the Scottish Council of Deans for Education, leading the expert sub-committee focusing on STEM/STEAM education.

Prof. Hutchison is responsible for leading nano safety research at the University with the aim of identifying whether a variety of nano-forms can enter the human body, interact with the respiratory, immune, and reproductive systems and cause harm. Prof Hutchison was submitted to RAE 2008, REF2014 and REF2021 and has secured and contributed to large collaborative nanotoxicology studies such as the EU FP7 projects ENPRA, ENRHES & MARINA and Horizon2020 BIORIMA project.

Themes

Esteem

Advisory panels and expert committees or witness

  • Member of the Scottish Government Chemicals Policy Network
  • Member of Register of Specialists UK Gov Officefor Product Safety & Standards
  • Member of FSA Register of Specialists
  • Member of the Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment, UK Food Standards Agency
  • Member of the Scottish Council of Deans of Education
  • Chair of the SIPR Board of Governance
  • Member of Defra’s College of Scientific Experts
  • Member of Hazardous Substances Advisory Committee

 

Grant Funding Panel Member

  • Panel Chair: Carnegie Trust for the Universities of Scotland - Research Incentive Grants 2019

 

Date


41 results

Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development.

Journal Article
Girardi, G., Fraser, J. A., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015)
Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. Molecular Psychiatry, 20, 1017-1026. https://doi.org/10.1038/mp.2014.110
In the current study, we have developed a magnetic resonance imaging-based method for non-invasive detection of complement activation in placenta and foetal brain in vivo in u...

In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome

Conference Proceeding
Girardi, G., Fraser, J., Bertolaccini, M. L., Lennen, R., Vontell, R., & Hutchison, G. (2014)
In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome. https://doi.org/10.1016/j.placenta.2014.06.184
Objectives: To use MRI-based methods to non invasively detect placental insufficiency and predict fetal outcomes in obstetric antiphospholipid syndrome (APS) Methods and resul...

Current In Vitro models for nanomaterial testing: The reproductive system.

Book Chapter
Hutchison, G., & Ross, B. (2014)
Current In Vitro models for nanomaterial testing: The reproductive system. In Nanotoxicology: Progress toward Nanomedicine, 357-372. (Second Edition). CRC Press (Taylor and Francis Group
No abstract available.

In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers.

Journal Article
Kermanizadeh, A., Pojana, G., Gaiser, B. K., Birkedal, R., Bilanicˇová, D., Wallin, H., …Stone, V. (2013)
In vitro assessment of engineered nanomaterials using a hepatocyte cell line: cytotoxicity, pro-inflammatory cytokines and functional markers. Nanotoxicology, 7, 301-313. https://doi.org/10.3109/17435390.2011.653416
Effects on the liver C3A cell line treated with a panel of engineered nanomaterials (NMs) consisting of two zinc oxide particles (ZnO; coated 100 nm and uncoated 130 nm), two ...

Engineered Nanomaterial Impact in the Liver following Exposure via an Intravenous Route–The Role of Polymorphonuclear Leukocytes and Gene Expression in the Organ

Journal Article
Kermanizadeh, A., Brown, D. M., Hutchison, G. R., & Stone, V. (2012)
Engineered Nanomaterial Impact in the Liver following Exposure via an Intravenous Route–The Role of Polymorphonuclear Leukocytes and Gene Expression in the Organ. Journal of Nanomedicine and Nanotechnology, 4, 157. https://doi.org/10.4172/2157-7439.1000157
Background and methods: Following exposure via a number of routes (inhalation, ingestion or injection), some Nanomaterials (NMs) translocate to secondary tissues, prominently ...

An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials

Journal Article
Kermanizadeh, A., Gaiser, B. K., Hutchison, G. R., & Stone, V. (2012)
An in vitro liver model - assessing oxidative stress and genotoxicity following exposure of hepatocytes to a panel of engineered nanomaterials. Particle and fibre toxicology, 9(1), 28. https://doi.org/10.1186/1743-8977-9-28
Background: Following exposure via inhalation, intratracheal instillation or ingestion some nanomaterials (NM) have been shown to translocate to the liver. Since oxidative str...

Comparison of the macrophage cell line NR8383 with primary lung macrophages

Journal Article
Wessels, A., Daly, P., Somers, G., Stone, V., Hutchison, G., & Hassall, D. (2012)
Comparison of the macrophage cell line NR8383 with primary lung macrophages. Toxicology Letters, 211, S108. https://doi.org/10.1016/j.toxlet.2012.03.403

Nanoparticles and Neutrophil Activation

Presentation / Conference
Dickson, C., Prach, M., Fraser, J., Ingram, L., Barlow, P., Hutchison, G., …Malone, E. (2012, February)
Nanoparticles and Neutrophil Activation. Presented at NanoImpactNet-QNANO conference - European Network on the Health and Environmental Impact of Nanomaterials, Dublin, Ireland
Neutrophils, the rapid responders of the innate immune system, are central to the initial immune responses of a host to foreign particles. Circulating in the blood, they are t...

Nanotoxicity.

Book Chapter
Hutchison, G. R., & Malone, E. M. (2011)
Nanotoxicity. In B. Booß-Bavnbek, B. Klösgen, J. Larsen, F. Pociot, & E. Renström (Eds.), Systems Biology of Regulated Exocytosis in Pancreatic β-Cells, 419-434. Springer. https://doi.org/10.1007/978-1-4419-6956-9_18
Nanotechnology, including the field of nanomedicine, promises to revolutionise/improve the way in which we live our lives. This atomic, molecular and macromolecular technology...

Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability: DBP effects on foetal germ cells

Journal Article
Jobling, M. S., Hutchison, G. R., van den Driesche, S., & Sharpe, R. M. (2011)
Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability: DBP effects on foetal germ cells. International Journal of Andrology, 34(5pt2), e386-e396. https://doi.org/10.1111/j.1365-2605.2010.01140.x
Environmental factors are implicated in increased incidence of human testicular germ‐cell cancer (TGCC). TGCC has foetal origins and may be one component of a testicular dysge...

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