Research Output
Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania
  Livestock abortion is an important cause of productivity losses worldwide and many infectious causes of abortion are zoonotic pathogens that impact on human health. Little is known about the relative importance of infectious causes of livestock abortion in Africa, including in subsistence farming communities that are critically dependent on livestock for food, income, and wellbeing. We conducted a prospective cohort study of livestock abortion, supported by cross-sectional serosurveillance, to determine aetiologies of livestock abortions in livestock in Tanzania. This approach generated several important findings including detection of a Rift Valley fever virus outbreak in cattle; high prevalence of C. burnetii infection in livestock; and the first report of Neospora caninum, Toxoplasma gondii, and pestiviruses associated with livestock abortion in Tanzania. Our approach provides a model for abortion surveillance in resource-limited settings. Our findings add substantially to current knowledge in sub-Saharan Africa, providing important evidence from which to prioritise disease interventions.

  • Type:

    Article

  • Date:

    08 July 2022

  • Publication Status:

    Published

  • DOI:

    10.1038/s41598-022-15517-8

  • Funders:

    The University of Edinburgh; Biotechnology and Biological Sciences Research Council; National Science Foundation

Citation

Thomas, K. M., Kibona, T., Claxton, J. R., de Glanville, W. A., Lankester, F., Amani, N., …Allan, K. J. (2022). Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania. Scientific Reports, 12(1), Article 11669. https://doi.org/10.1038/s41598-022-15517-8

Authors

Monthly Views:

Available Documents
  • pdf

    Prospective cohort study reveals unexpected aetiologies of livestock abortion in northern Tanzania

    1MB

    Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

  • Downloadable citations

    HTML BIB RTF