Date


Themes

Output Type

Download Available

77 results

The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions

Working Paper
Lankester, F., Kibona, T. J., Allan, K. J., de Glanville, W., Buza, J. J., Katzer, F., …Cleaveland, S. (2024)
The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions
Background: Lack of reliable data on the aetiology of livestock diseases, especially in Africa, is a major factor constraining the design of effective livestock health interve...

Seroprevalence and risk factors for Q-fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania

Journal Article
Festo Bwatota, S., Mkilema Shirima, G., Hernandez-Castro, L. E., Mark de Clare Bronsvoort, B., Wheelhouse, N., Joseph Mengele, I., …Cook, E. A. J. (2022)
Seroprevalence and risk factors for Q-fever (Coxiella burnetii) exposure in smallholder dairy cattle in Tanzania. Veterinary Sciences, 9(12), Article 662. https://doi.org/10.3390/vetsci9120662
Q fever is a zoonotic disease, resulting from infection with Coxiella burnetii. Infection in cattle can cause abortion and infertility, however, there is little epidemiologica...

Epidemiology of q-fever in domestic ruminants and humans in Africa: A systematic review

Journal Article
Festo Bwatota, S., Cook, E. A. J., Mark de Clare Bronsvoort, B., Wheelhouse, N., Hernandez-Castor, L. E., & Mkilema Shirima, G. (2022)
Epidemiology of q-fever in domestic ruminants and humans in Africa: A systematic review. CABI One Health, https://doi.org/10.1079/cabionehealth.2022.0008
Q-fever is a zoonotic infectious disease caused by the gram-negative, intracellular, spore-forming bacterium Coxiella burnetii. Infected ruminants (cattle, sheep, and goats) a...

Endemicity of Coxiella burnetii infection among people and their livestock in pastoral communities in northern Kenya

Journal Article
Muema, J., Nyamai, M., Wheelhouse, N., Njuguna, J., Jost, C., Oyugi, J., …Thumbi, S. (2022)
Endemicity of Coxiella burnetii infection among people and their livestock in pastoral communities in northern Kenya. Heliyon, 8(10), Article e11133. https://doi.org/10.1016/j.heliyon.2022.e11133
Background Coxiella burnetti can be transmitted to humans primarily through inhaling contaminated droplets released from infected animals or consumption of contaminated dairy ...

Modelling the Transmission of Coxiella burnetii within a UK Dairy Herd: Investigating the Interconnected Relationship between the Parturition Cycle and Environment Contamination

Journal Article
Patsatzis, D. G., Wheelhouse, N., & Tingas, E. (2022)
Modelling the Transmission of Coxiella burnetii within a UK Dairy Herd: Investigating the Interconnected Relationship between the Parturition Cycle and Environment Contamination. Veterinary Sciences, 9(10), Article 522. https://doi.org/10.3390/vetsci9100522
Q fever infection in dairy herds is introduced through the transmission of the bacterium Coxiella burnetii, resulting in multiple detrimental effects such as reduction of lact...

Editorial: New Approaches to Understanding Vector Borne Diseases in Domestic and Wild animals

Journal Article
Cook, E. A., Wheelhouse, N., Larska, M., & Obanda, V. (2022)
Editorial: New Approaches to Understanding Vector Borne Diseases in Domestic and Wild animals. Frontiers in Veterinary Science, 9, Article 1009751. https://doi.org/10.3389/fvets.2022.1009751

Recent advances and public health implications for environmental exposure to Chlamydia abortus: from enzootic to zoonotic disease

Journal Article
Turin, L., Surini, S., Wheelhouse, N., & Silvia Rocchi, M. (2022)
Recent advances and public health implications for environmental exposure to Chlamydia abortus: from enzootic to zoonotic disease. Veterinary Research, 53(1), Article 37. https://doi.org/10.1186/s13567-022-01052-x
Environmental transmission of Chlamydia abortus as a result of enzootic disease or disease outbreaks and the threats posed by this pathogen has been previously reported, howev...

Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle

Journal Article
Wheelhouse, N., Hearn, J., Livingstone, M., Flockhart, A., Dagleish, M., & Longbottom, D. (2022)
Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle. Journal of Applied Microbiology, 132(4), 2642-2648. https://doi.org/10.1111/jam.15422
Aims The order Chlamydiales comprises a broad range of bacterial pathogens and endosymbionts, which infect a wide variety of host species. Within this order, members of the fa...

Q fever and early pregnancy failure: a Scottish case control study

Journal Article
Wheelhouse, N., Kemp, S., Halliday, J. E. B., Tingas, E. A., Duncan, W. C., & Horne, A. W. (2022)
Q fever and early pregnancy failure: a Scottish case control study. Reproduction and Fertility, 3(1), https://doi.org/10.1530/raf-21-0072

Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion

Journal Article
Livingstone, M., Ranjan Wattegedera, S., Palarea-Albaladejo, J., Aitchison, K., Corbett, C., Sait, M., …Longbottom, D. (2021)
Efficacy of two Chlamydia abortus subcellular vaccines in a pregnant ewe challenge model for ovine enzootic abortion. Vaccines, 9(8), Article 898. https://doi.org/10.3390/vaccines9080898
Chlamydia abortus, the aetiological agent of enzootic abortion of ewes, is a major cause of reproductive loss in small ruminants worldwide, accounting for significant economic...
11 results

Tackling bottlenecks to the use of Johne’s Disease data and adding value to increase farmer and vet engagement in Johne’s disease control

2022 - 2023
Tackling bottlenecks to the use of Johne’s Disease data and adding value to increase farmer and vet engagement in Johne’s disease control
Funder: Biotechnology and Biological Sciences Research Council | Value: £24,699

Virulence of diverse Listeria monocytogenes strains in an invertebrate infection model

2022 - 2022
Listeria monocytogenes (L. monocytogenes) is a bacterium which is found throughout the environment and is the cause of listeriosis, a major food-borne disease. While annual case numbers are relatively...
Funder: Medical Research Scotland | Value: £2,160

Management of post-weaning diarrhoea and the implications for AMR in response to the upcoming ban on zinc supplementation in pigs

2022 - 2023
Management of post-weaning diarrhoea and the implications for AMR in response to the upcoming ban on zinc supplementation in pigs
Funder: Biotechnology and Biological Sciences Research Council | Value: £4,170

Investigating the prevalence and diversity of bacterial endosymbionts in Scottish hoverfly populations

2021 - 2022
Investigating the prevalence and diversity of bacterial endosymbionts in Scottish hoverfly populations
Funder: Carnegie Trust for the Universities of Scotland | Value: £13,549

EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya

2019 - 2019
EEID travel award: Understanding transmission dynamics for bacterial zoonoses in humans, goats and camels among pastoral communities in Northern Kenya
Funder: Biotechnology and Biological Sciences Research Council | Value: £1,960

Rutherford fund Strategic Partner Grant

2018 - 2019
Rutherford Fellows, will work in project areas related to food safety (Pathogen detection, AMR etc) and food spoilage. Rutherford Fund, are funded by BEIS and the scheme is being managed by Universit...
Funder: Department for Business, Energy & Industrial Strategy | Value: £39,800

Direct and paracrine effects of Chlamydia infection on decidualisation of endometrial stromal cells

2018 - 2018
SRF summer studentship
Funder: Society for Reproduction and Fertility | Value: £2,750

Mechanism of Chlamydia induced progesterone resistance

2018 - 2019
Chlamydia trachomatis is the most common sexually-transmitted infection in the world, and is associated with miscarriage, pre-term birth and infertility. However, the understanding of the mechanisms t...
Funder: Society for Reproduction and Fertility | Value: £12,034

Development of a UV-C hand-sanitiser unit

2017 - 2017
Development of a UV-C hand-sanitiser unit
Funder: Scottish Funding Council | Value: £5,000

Acceptability of extragenital Chlamydia testing

2017 - 2018
Chlamydia trachomatis is the most common sexually transmitted infection in Scotland, and has significant long‐term consequences to reproductive health. Recent studies suggest that in addition to the g...
Funder: Chief Scientists Office | Value: £27,998
9 results

Do nanomedicines have the potential to combat antimicrobial resistance?

2022 - date
Bah Umaru | Director of Studies: Dr Nick Wheelhouse | Second Supervisor: Dr Samantha Donnellan

Manipulation of the plant microbiome to improve the quality and safety of fresh plant produce.

2021 - date
Adam Wareing | Director of Studies: Prof Ian Singleton | Second Supervisor: Dr Nick Wheelhouse

Developing gregarine apicomplexans as aquatic symbiosis model system

2020 - date
Kevin Mckinley | Director of Studies: Dr Nick Wheelhouse

Design and development of novel targeted anticancer drugs

2018 - date
Ewoma Akpughe | Director of Studies: Dr David Mincher | Second Supervisor: Agnes Turnbull

Determination of virulence of L. monocytogenes strains of environmental and food sources using an invertebrate model

2018 - 2020
Bah Umaru | Director of Studies: Dr Nick Wheelhouse | Second Supervisor: Prof Ian Singleton

Sources and survival of listeria monocytogenes on fresh, leafy produce

2016 - 2020
Listeria monocytogenes is a ubiquitous environmental bacterium which has the potential to cause serious illness and even death aft...
Alva Smith | Director of Studies: Prof Ian Singleton | Second Supervisor: Dr Clare Taylor

Cationic Host Defence Peptides as novel therapeutics for Chlamydia infection

2016 - 2018
Beatriz Cozar Fernandez | Director of Studies: Prof Peter Barlow | Second Supervisor: Dr Nick Wheelhouse

Endometrial dysfunction as a result of Chlamydial infection

2016 - 2018
Megan Brown | Director of Studies: Dr Nick Wheelhouse | Second Supervisor: Prof Mick Rae

Multi-scale habitat selection in Scotland's only popularion of western Taiga Bean Geese, Anser fabalis fabalis, on the Slamanna Plateau, central Scotland.

2015 - 2018
Michael Thornton | Director of Studies: Dr Patrick White | Second Supervisor: Prof Robert Briers