A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics
Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Peters, S., Hankin, S., Aschberger, K., & Stone, V. (2010)
A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics. Nanotoxicology, 4(2), 207-246. https://doi.org/10.3109/17435390903569639
This critical review of the available human health safety data, relating to carbon nanotubes (CNTs), was conducted in order to assess the risks associated with CNT exposure. D...
A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity
Journal Article
Johnston, H. J., Hutchison, G., Christensen, F. M., Peters, S., Hankin, S., & Stone, V. (2010)
A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity. Critical Reviews in Toxicology, 40(4), 328-346. https://doi.org/10.3109/10408440903453074
This review is concerned with evaluating the toxicity associated with human exposure to silver and gold nanoparticles (NPs), due to the relative abundance of toxicity data ava...
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation
Journal Article
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007)
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), 80-89. https://doi.org/10.1016/j.taap.2007.07.012
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...
Androgen action in the masculinization programming window and development of male reproductive organs
Journal Article
MacLeod, D. J., Sharpe, R. M., Welsh, M., Fisken, M., Scott, H. M., Hutchison, G. R., …van den Driesche, S. (2010)
Androgen action in the masculinization programming window and development of male reproductive organs. International Journal of Andrology, 33(2), 279-287. https://doi.org/10.1111/j.1365-2605.2009.01005.x
We have shown previously that deficient androgen action within a masculinization programming window (MPW; e15.5–e18.5 in rats) is important in the origin of male reproductive ...
Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1
Journal Article
Hutchison, G. R., Scott, H. M., Walker, M., McKinnell, C., Ferrara, D., Mahood, I. K., & Sharpe, R. M. (2008)
Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1. Biology of Reproduction, 78(2), 352-360. https://doi.org/10.1095/biolreprod.107.064006
Pregnancy exposure to di(n-butyl) phthalate (DBP) in rats induces a testicular dysgenesislike syndrome (TDS) in male offspring. Earlier studies suggested altered Sertoli cell ...
In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome
Conference Proceeding
Girardi, G., Fraser, J., Bertolaccini, M. L., Lennen, R., Vontell, R., & Hutchison, G. (2014)
In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome. https://doi.org/10.1016/j.placenta.2014.06.184
Objectives: To use MRI-based methods to non invasively detect placental insufficiency and predict fetal outcomes in obstetric antiphospholipid syndrome (APS)
Methods and resul...
Socio-environmental Health. Exploring risk and resource spaces within urban environments. An interdisciplinary enquiry.
Presentation / Conference
Carnegie, E., Reid, A., Deakin, M., & Inglis, G. (2018, September)
Socio-environmental Health. Exploring risk and resource spaces within urban environments. An interdisciplinary enquiry. Paper presented at Space and Poverty (Salzburg Conference in Interdisciplinary Poverty Research
Regenerative spaces (good for health, environment and the planet) are essential for human flourishing. Findings from previous research suggest an association between spatial p...
Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development
Journal Article
Drake, A. J., van den Driesche, S., Scott, H. M., Hutchison, G. R., Seckl, J. R., & Sharpe, R. M. (2009)
Glucocorticoids Amplify Dibutyl Phthalate-Induced Disruption of Testosterone Production and Male Reproductive Development. Endocrinology, 150(11), 5055-5064. https://doi.org/10.1210/en.2009-0700
Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal te...
Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration
Journal Article
Barlow, P., Donaldson, K., MacCallum, J., Clouter, A., & Stone, V. (2005)
Serum exposed to nanoparticle carbon black displays increased potential to induce macrophage migration. Toxicology Letters, 155(3), 397-401. https://doi.org/10.1016/j.toxlet.2004.11.006
Objective:
To assess whether fine and ultrafine particles (nanoparticles) have the capacity to activate factors in serum that would induce macrophage migration. This is a mode...
Is Population Density Associated with Non-Communicable Disease in Western Developed Countries? A Systematic Review
Journal Article
Carnegie, E. R., Inglis, G., Taylor, A., Bak-Klimek, A., & Okoye, O. (2022)
Is Population Density Associated with Non-Communicable Disease in Western Developed Countries? A Systematic Review. International Journal of Environmental Research and Public Health, 19(5), https://doi.org/10.3390/ijerph19052638
Over the last three decades, researchers have investigated population density and health outcomes at differing scale. There has not been a systematic review conducted in order...