The Ex Vivo Organ Culture of Bone
Book Chapter
Staines, K. A., Brown, G., & Farquharson, C. (2019)
The Ex Vivo Organ Culture of Bone. In Bone Research Protocols (199-215). New york, USA: Humana Press. https://doi.org/10.1007/978-1-4939-8997-3_10
The ex vivo organ culture of bone provides many of the advantages of both the whole organism and isolated cell strategies and can deliver valuable insight into the network of ...
Antiviral host defence peptides.
Book Chapter
Sousa, F. H., Casanova, V., Stevens, C., & Barlow, P. G. (2016)
Antiviral host defence peptides. In R. M. Epand (Ed.), Host Defense Peptides and Their Potential as Therapeutic Agents, 57-94. Springer Verlag. https://doi.org/10.1007/978-3-319-32949-9_3
The on going global mortality and morbidity associated with viral pathogens highlights the need for the continued development of effective, novel antiviral molecules. The anti...
Regulation and Function of the Original p53- Inducible p21 Gene
Book Chapter
Fraser, J. A. (2010)
Regulation and Function of the Original p53- Inducible p21 Gene. In p53; Molecular Biology Intelligence Unit, 100-116. Springer Science + Business Media. https://doi.org/10.1007/978-1-4419-8231-5_7
P21 is a well known regulator of cell cycle progression through its inhibitory actions on Cyclin dependent kinases, (Cdk)/cyclin complexes, and DNA replication via its binding...
Applied anatomy and physiology and the renal disease process
Book Chapter
Chalmers, C. (2019)
Applied anatomy and physiology and the renal disease process. In Renal nursing: Care and management of people with kidney disease, 21-58. (5). Wiley. https://doi.org/10.1002/9781119413172.ch2
This chapter provides the reader with a detailed discussion of all aspects of renal physiology and its relationship to important pathophysiological processes in renal disease,...
The Isolation of Genomic DNA from Invertebrates
Book Chapter
Vreugdenhil, E., & Darlison, M. G. (1992)
The Isolation of Genomic DNA from Invertebrates. In A. Longstaff, & P. Revest (Eds.), Protocols in Molecular Neurobiology, 15-24. Springer Verlag. https://doi.org/10.1385/0-89603-199-3%3A15
Generally, genomic DNA is used either for the construction of genomic libraries or for Southern blot analysis. For several reasons, it is frequently preferable in the field of...
Molluscan ligand-gated ion-channel receptors
Book Chapter
Darlison, M. G., Hutton, M. L., & Harvey, R. J. (1993)
Molluscan ligand-gated ion-channel receptors. In Comparative Molecular Neurobiology, 48-64. Springer Verlag. https://doi.org/10.1007/978-3-0348-7265-2_3
In this chapter we introduce the reader to the structures of the different types of ligand-gated ion-channel receptor, and the numerous receptor subtypes that have recently be...
Capsular Polysaccharides and Their Role in Virulence
Book Chapter
Taylor, C. M., & Roberts, I. S. (2004)
Capsular Polysaccharides and Their Role in Virulence. In W. Russell, & H. Herwald (Eds.), Concepts in Bacterial Virulence; Contributions to Microbiology, 55-66. Karger Publishers. https://doi.org/10.1159/000081689
No abstract available.
The ‘Chicken and Egg’ Problem of Co-evolution of Peptides and Their Cognate Receptors: Which Came First?
Book Chapter
Darlison, M. G., & Richter, D. (1999)
The ‘Chicken and Egg’ Problem of Co-evolution of Peptides and Their Cognate Receptors: Which Came First?. In D. Richter (Ed.), Regulatory Peptides and Cognate Receptors (1-11). Berlin: Springer. https://doi.org/10.1007/978-3-540-49421-8_1
As will be evident from the other chapters in this Volume, small peptide molecules regulate a wide variety of biological processes in both vertebrate and invertebrate species....
The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies
Book Chapter
Darlison, M. G., Barnard, E. A., Bateson, A. N., Glencorse, T. A., Harvey, R. J., Hicks, A. A., …Wisden, W. (1989)
The Structure and Expression of the GABAA Receptor as Deduced by Molecular Genetic Studies. In Molecular Biology of Neuroreceptors and Ion Channels, 83-99. Springer Verlag. https://doi.org/10.1007/978-3-642-74155-5_7
It is well established that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) mediates many of its effects by binding to the GABAA receptor, which is present on the m...
Regulation of capsule expression
Book Chapter
Taylor, C., & Roberts, I. S. (2010)
Regulation of capsule expression. In . M. Wilson (Ed.), Bacterial Adhesion to Host Tissues: Mechanisms and Consequences, (115-138). Cambridge: Cambridge University Press
No abstract available.