Genome sequence of the Chlamydophila abortus variant strain LLG
Journal Article
Sait, M., Clark, E. M., Wheelhouse, N., Livingstone, M., Spalding, L., Siarkou, V. I., …Longbottom, D. (2011)
Genome sequence of the Chlamydophila abortus variant strain LLG. Journal of Bacteriology, 193(16), 4276-4277. https://doi.org/10.1128/JB.05290-11
Chlamydophila abortus is a common cause of ruminant abortion. Here we report the genome sequence of strain LLG, which differs genotypically and phenotypically from the wild-ty...
Transcriptional analysis of in vitro expression patterns of chlamydophila abortus polymorphic outer membrane proteins during the chlamydial developmental cycle.
Journal Article
Wheelhouse, N., Aitchison, K., Spalding, L., Livingstone, M., & Longbottom, D. (2009)
Transcriptional analysis of in vitro expression patterns of chlamydophila abortus polymorphic outer membrane proteins during the chlamydial developmental cycle. Veterinary Research, 40(5), 47. https://doi.org/10.1051/vetres/2009030
Chlamydophila abortus is the aetiological agent of ovine enzootic abortion. Sequencing, annotation and comparative analysis of the genome of C. abortus strain S26/3 has reveal...
Chlamydia in cases of bovine abortion in Ireland
Journal Article
Wheelhouse, N., Longbottom, D., & O'Donovan, J. (2014)
Chlamydia in cases of bovine abortion in Ireland. Veterinary Record, 174(22), 560-561. https://doi.org/10.1136/vr.g3567
We report the findings of a preliminary investigation into chlamydial involvement in cases of bovine abortion in Ireland. Chlamydia abortus has long been recognised as a known...
Growth hormone and amino acid supply interact synergistically to control insulin-like growth factor-I production and gene expression in cultured ovine hepatocytes.
Journal Article
Wheelhouse, N. M., Stubbs, A. K., Lomax, M. A., & MacRae, J. C. (1999)
Growth hormone and amino acid supply interact synergistically to control insulin-like growth factor-I production and gene expression in cultured ovine hepatocytes. Journal of Endocrinology, 163(2), 353-361. https://doi.org/10.1677/joe.0.1630353
Many of the anabolic effects of growth hormone (GH) are indirect, occurring through GH-stimulated production of insulin-like growth factor-I (IGF-I) by the liver. As well as b...
Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract
Journal Article
Wheelhouse, N., Wattegedera, S., Fleming, D., Fitch, P., Kelly, R., & Entrican, G. (2008)
Chlamydia trachomatis and Chlamydophila abortus induce the expression of secretory leukocyte protease inhibitor in cells of the human female reproductive tract. Microbiology and Immunology, 52(9), 465-468. https://doi.org/10.1111/j.1348-0421.2008.00058.x
C. trachomatis and C. abortus are related Gram-negative intracellular bacteria that cause reproductive failure due to infertility (C. trachomatis) or abortion (C. abortus). Th...
Evaluation of the impact and control of enzootic abortion of ewes
Journal Article
Longbottom, D., Entrican, G., Wheelhouse, N., Brough, H., & Milne, C. (2013)
Evaluation of the impact and control of enzootic abortion of ewes. Veterinary Journal, 195(2), 257-259. https://doi.org/10.1016/j.tvjl.2012.06.018
Despite the availability of effective management and treatment strategies, Chlamydia abortus remains the single most frequently diagnosed cause of infectious ovine abortion (e...
Ferlavirus-related deaths in a collection of viperid snakes
Journal Article
Flach, E. J., Dagleish, M. P., Feltrer, Y., Gill, I. S., Marschang, R. E., Masters, N., …Wheelhouse, N. M. (2018)
Ferlavirus-related deaths in a collection of viperid snakes. Journal of Zoo and Wildlife Medicine, 49(4), 983-995. https://doi.org/10.1638/2017-0223.1
Between June and October 2013 26 snakes of six viperid species kept in two adjoining rooms died (n = 16) or were euthanized on medical (1) or welfare grounds (9). Two were fro...
Immunity in the female sheep reproductive tract.
Journal Article
Entrican, G. & Wheelhouse, N. M. (2006)
Immunity in the female sheep reproductive tract. Veterinary Research. 37(3), 295-309. doi:10.1051/vetres:2006002. ISSN 0928-4249
Immune surveillance in the female reproductive tract is dependent on the interplay of many factors that include the expression of pattern recognition receptors on epithelial c...
Effect of high-fat enteral nutrition on hepatocyte injury in response to hemorrhagic shock in the rat.
Journal Article
Chu, M. M., Luyer, M. D. P., Wheelhouse, N. M., Bellamy, C. O., Greve, J. W. M., Buurman, W. A., …Wigmore, S. J. (2007)
Effect of high-fat enteral nutrition on hepatocyte injury in response to hemorrhagic shock in the rat. World Journal of Surgery. 31(8), 1693-1701. doi:10.1007/s00268-007-9107-2. ISSN 0364-2313
BACKGROUND: High-fat enteral nutrition reduces the inflammatory response following hemorrhagic shock in the rat. AIMS: We hypothesized that this intervention might also amelio...
Chlamydia in cases of cattle pneumonia in Scotland
Journal Article
Wheelhouse, N., Longbottom, D., & Willoughby, K. (2013)
Chlamydia in cases of cattle pneumonia in Scotland. Veterinary Record, 172(4), 110. https://doi.org/10.1136/vr.f469