Sharron Vass

Sharron Vass

Dr Sharron Vass BSc. Hons., PhD, FHEA

Lecturer

Biography

Dr Sharron Vass is a lecturer of Biomedical Sciences in the School of Applied Sciences, at Edinburgh Napier University, Scotland, UK.

In 2005, Dr Vass completed her Ph.D. studies in the Institute of Cell and Molecular Biology, University of Edinburgh, under the direction of Professor Margarete Heck. Her project involved investigating the molecular ‘glue’ that holds chromosomes together and what happens to chromosome structure when that glue is absent. Through this project she developed a keen interest in cell biology and a passion for fluorescence microscopy.

Dr Vass then undertook post-doctoral research at the Queen’s Medical Research Institute, University of Edinburgh, where she was involved in the study of a metalloproteinase enzyme called Invadolysin. She discovered that when the Invadolysin enzyme was ‘silenced’ in zebrafish embryos there were defects in essential cell migration processes, such as formation of blood vessels and the migration of specialised cells called neuromasts and melanophores.

Dr Vass obtained a lectureship at Edinburgh Napier University in 2014, where she established her own research group focusing on the molecular pathways regulating cell migration in cancer cells. She uses highly migratory melanoma cells and human choriocarcinoma cells as model systems, and is particularly interested in the KISS1 / KISS1R signalling cascade.

Themes

Research Areas

Esteem

Advisory panels and expert committees or witness

  • Co- Chair, Little France Post-Doctoral Society

 

Conference Activity

  • Beatson International Cancer Conference, Glasgow

 

Fellowships and Awards

  • Fellow of the Higher Education Academy

 

Invited Speaker

  • Soapbox Science - Public Engagement Event, The Mound, Edinburgh
  • Monster Confidence - STEM Promotion, Heriot Watt Uinversity, Edinburgh
  • Taking the Sticky out of Cohesion, University of Dundee
  • Linking Cell Migration and Angiogenesis in Zebrafish, University of Glasgow
  • Linking Cell Migration and Angiogenesis in Zebrafish, University of Sheffield
  • Winner - 3 Minute Thesis (2016), School of Applied Sciences, Edinburgh Napier University
  • Imaging Vascular Development and Cell Migration in Zebrafish, Karolinska Institute, Sweden
  • From Flies to Fish (via humans), Centre for Cardiovascular Research, University of Edinburgh

 

Membership of Professional Body

  • Member of British Society for Cell Biology

 

Date


15 results

Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis

Journal Article
Valdeolmillos, A., Rufas, J. S., Suja, J. A., Vass, S., Heck, M. M., Martínez-A, C., & Barbero, J. L. (2004)
Drosophila cohesins DSA1 and Drad21 persist and colocalize along the centromeric heterochromatin during mitosis. Biology of the Cell, 96(6), 457-462. doi:10.1016/j.biolcel.2004.04.011
Sister chromatid cohesion in eukaryotes is maintained mainly by a conserved multiprotein complex termed cohesin. Drad21 and DSA1 are the Drosophila homologues of the yeast Scc...

Depletion of Drad21/Scc1 in Drosophila Cells Leads to Instability of the Cohesin Complex and Disruption of Mitotic Progression

Journal Article
Vass, S., Cotterill, S., Valdeolmillos, A. M., Barbero, J. L., Lin, E., Warren, W. D., & Heck, M. M. (2003)
Depletion of Drad21/Scc1 in Drosophila Cells Leads to Instability of the Cohesin Complex and Disruption of Mitotic Progression. Current Biology, 13(3), 208-218. doi:10.1016/S0960-9822(03)00047-2
Background: The coordination of cell cycle events is necessary to ensure the proper duplication and dissemination of the genome. In this study, we examine the consequences of ...

Loss of Cell Cycle Checkpoint Control in Drosophila Rfc4 Mutants

Journal Article
Krause, S. A., Loupart, M., Vass, S., Schoenfelder, S., Harrison, S., & Heck, M. M. S. (2001)
Loss of Cell Cycle Checkpoint Control in Drosophila Rfc4 Mutants. Molecular and Cellular Biology, 21(15), 5156-5168. doi:10.1128/mcb.21.15.5156-5168.2001
Two alleles of the Drosophila melanogaster Rfc4(DmRfc4) gene, which encodes subunit 4 of the replication factor C (RFC) complex, cause striking defects in mitotic chromosome c...

A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis

Journal Article
Steffensen, S., Coelho, P. A., Cobbe, N., Vass, S., Costa, M., Hassan, B., …Sunkel, C. E. (2001)
A role for Drosophila SMC4 in the resolution of sister chromatids in mitosis. Current Biology. 11(5), 295-307. doi:10.1016/s0960-9822(01)00096-3. ISSN 0960-9822
Background: Faithful segregation of the genome during mitosis requires interphase chromatin to be condensed into well-defined chromosomes. Chromosome condensation involves a m...

Mutations in the Drosophila SMC4 gene are associated with abnormal mitotic chromosome segregation

Journal Article
Cobbe, N., Steffensen, S., Vass, S., Coelho, P., Hassan, B., Bellen, H., …Heck, M. S. (2000)
Mutations in the Drosophila SMC4 gene are associated with abnormal mitotic chromosome segregation. Biochemical Society Transactions, 28(5), A246.2-A246. https://doi.org/10.1042/bst028a246a

Pre-Napier Funded Projects

  • Pump-Priming Award, BHF

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