New developments in osteoarthritis and cartilage biology
Journal Article
Poulet, B., & Staines, K. A. (2016)
New developments in osteoarthritis and cartilage biology. Current Opinion in Pharmacology, 28, 8-13. https://doi.org/10.1016/j.coph.2016.02.009
Osteoarthritis (OA) is a degenerative joint disease and the most common form of arthritis. Characterised by articular cartilage loss, subchondral bone thickening and osteophyt...
Cartilage development and degeneration: a Wnt Wnt situation - cartilage development and degeneration: a WNT WNT situation
Journal Article
Staines, K. A., MacRae, V. E., & Farquharson, C. (2012)
Cartilage development and degeneration: a Wnt Wnt situation - cartilage development and degeneration: a WNT WNT situation. Cell Biochemistry and Function, 30(8), 633-642. https://doi.org/10.1002/cbf.2852
The Wnt signaling pathway plays a crucial role in the development and homeostasis of a variety of adult tissues and, as such, is emerging as an important therapeutic target fo...
The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling
Journal Article
Staines, K. A., MacRae, V. E., & Farquharson, C. (2012)
The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling. Journal of Endocrinology, 214(3), 241-255. https://doi.org/10.1530/joe-12-0143
The small integrin-binding ligand N-linked glycoprotein (SIBLING) family consists of osteopontin, bone sialoprotein, dentin matrix protein 1, dentin sialophosphoprotein and ma...