Peptide Combinatorial Libraries Identify TSC2 as a Death-associated Protein Kinase (DAPK) Death Domain-binding Protein and Reveal a Stimulatory Role for DAPK in mTORC1 Signaling
Journal Article
Stevens, C., Lin, Y., Harrison, B., Burch, L., Ridgway, R. A., Sansom, O. J., & Hupp, T. R. (2009)
Peptide Combinatorial Libraries Identify TSC2 as a Death-associated Protein Kinase (DAPK) Death Domain-binding Protein and Reveal a Stimulatory Role for DAPK in mTORC1 Signaling. Journal of Biological Chemistry, 284, 334-344. https://doi.org/10.1074/jbc.M805165200
Death-associated protein kinase (DAPK) is a multidomain enzyme that plays a central role in autophagic and apoptotic signaling, although the protein-protein interactions regul...
The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone.
Thesis
Behan, J. L. The binding ability of alpha-1-acid glycoprotein as a mechanism of resistance to methadone. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/4446
Dependence on heroin and other opioids represents a considerable problem worldwide. There is a continual need to improve therapy and/ or find more efficacious alternatives if...
Calcium and ROS-mediated activation of transcription factors and TNF-α cytokine gene expression in macrophages exposed to ultrafine particles
Journal Article
Brown, D. M., Donaldson, K., Borm, P. J., Schins, R. P., Dehnhardt, M., Gilmour, P., …Stone, V. (2004)
Calcium and ROS-mediated activation of transcription factors and TNF-α cytokine gene expression in macrophages exposed to ultrafine particles. American Journal of Physiology - Lung Cellular and Molecular Physiology, 286(2), L344-L353. https://doi.org/10.1152/ajplung.00139.2003
Ultrafine (Uf) particles are a component of particulate air pollution suggested to be responsible for the health effects associated with elevations of this pollutant. We have ...
The Ex Vivo Organ Culture of Bone
Book Chapter
Staines, K. A., Brown, G., & Farquharson, C. (2019)
The Ex Vivo Organ Culture of Bone. In Bone Research Protocols (199-215). New york, USA: Humana Press. https://doi.org/10.1007/978-1-4939-8997-3_10
The ex vivo organ culture of bone provides many of the advantages of both the whole organism and isolated cell strategies and can deliver valuable insight into the network of ...
Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis.
Journal Article
Lin, Y., Stevens, C., & Hupp, T. (2007)
Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. Journal of Biological Chemistry, 282(23), 16792-16802. https://doi.org/10.1074/jbc.M611559200
DAPK-1 is a stress-activated tumor suppressor protein that plays a role in both proapoptotic or antiapoptotic signal transduction pathways. To define mechanisms of DAPK-1 prot...
Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms
Journal Article
Proudfoot, L., Kusel, J. R., Smith, H. V., Harnett, W., Worms, M. J., & Kennedy, M. W. (1993)
Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms. Parasitology, 107(01), 107. doi:10.1017/s0031182000079464
All mammalian-parasitic stages of a range of nematode species investigated (Brugia pahangi, Acanthocheilonema viteae, Strongyloides ratti, Nippostrongylus brasiliensis, Trichi...
The influence of changes in nitrogen: silicon ratios on diatom growth dynamics
Journal Article
Gilpin, L., Davidson, K., & Roberts, E. (2004)
The influence of changes in nitrogen: silicon ratios on diatom growth dynamics. Journal of Sea Research, 51(1), 21-35. https://doi.org/10.1016/j.seares.2003.05.005
Nitrate loading to coastal waters has increased over recent decades while silicon loading has remained relatively constant or decreased. As the N:Si ratio in coastal waters sh...
Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae
Journal Article
Singleton, I., & Simmons, P. (1996)
Factors affecting silver biosorption by an industrial strain of Saccharomyces cerevisiae. Journal of Chemical Technology and Biotechnology, 65(1), 21-28. https://doi.org/10.1002/%28SICI%291097-4660%28199601%2965%3A13.0.CO%3B2-E
Factors affecting silver biosorption by Saccharomyces cerevisiae biomass, obtained as a waste product from industry, were examined. Maximum removal of silver from solution was...
Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae
Journal Article
Martínez-Pastor, M., De Llanos, R., Romero, A., & Puig, S. (2013)
Post-Transcriptional Regulation of Iron Homeostasis in Saccharomyces cerevisiae. International Journal of Molecular Sciences, 14(8), 15785-15809. https://doi.org/10.3390/ijms140815785
Iron is an essential micronutrient for all eukaryotic organisms because it participates as a redox cofactor in a wide variety of biological processes. Recent studies in Saccha...
Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824
Thesis
Almohaish, A. A. Characterisation of class II and III fructose bisphosphatases in Clostridium acetobutylicum ATCC 824. (Thesis)
Edinburgh Napier University. Retrieved from http://researchrepository.napier.ac.uk/id/eprint/5692
In low GC Gram-positive bacteria, the phenomenon of carbon catabolite repression is dependent on a metabolite-activated bifunctional protein kinase/phosphorylase. In Clostridi...