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A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics

Journal Article
Johnston, H. J., Hutchison, G. R., Christensen, F. M., Peters, S., Hankin, S., Aschberger, K., & Stone, V. (2010)
A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics. Nanotoxicology, 4(2), 207-246. https://doi.org/10.3109/17435390903569639
This critical review of the available human health safety data, relating to carbon nanotubes (CNTs), was conducted in order to assess the risks associated with CNT exposure. D...

A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity

Journal Article
Johnston, H. J., Hutchison, G., Christensen, F. M., Peters, S., Hankin, S., & Stone, V. (2010)
A review of the in vivo and in vitro toxicity of silver and gold particulates: Particle attributes and biological mechanisms responsible for the observed toxicity. Critical Reviews in Toxicology, 40(4), 328-346. https://doi.org/10.3109/10408440903453074
This review is concerned with evaluating the toxicity associated with human exposure to silver and gold nanoparticles (NPs), due to the relative abundance of toxicity data ava...

An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions

Journal Article
Smith, K., Muggeridge, D. J., Easton, C., & Ross, M. D. (2019)
An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions. European Journal of Applied Physiology, 119(3), 723-733. https://doi.org/10.1007/s00421-018-04063-9
Purpose: Dietary nitrate (NO3-) has repeatedly been shown to improve endurance and intermittent, high-intensity events in temperate conditions. However, the ergogenic effects...

Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation

Journal Article
Wilson, M. R., Foucaud, L., Barlow, P. G., Hutchison, G. R., Sales, J., Simpson, R. J., & Stone, V. (2007)
Nanoparticle interactions with zinc and iron: Implications for toxicology and inflammation. Toxicology and Applied Pharmacology, 225(1), 80-89. https://doi.org/10.1016/j.taap.2007.07.012
Particulate air pollution (PM10) consists of a mixture of components, including nanoparticles and metals. Studies from our laboratory have demonstrated that transition metals ...

Androgen action in the masculinization programming window and development of male reproductive organs

Journal Article
MacLeod, D. J., Sharpe, R. M., Welsh, M., Fisken, M., Scott, H. M., Hutchison, G. R., …van den Driesche, S. (2010)
Androgen action in the masculinization programming window and development of male reproductive organs. International Journal of Andrology, 33(2), 279-287. https://doi.org/10.1111/j.1365-2605.2009.01005.x
We have shown previously that deficient androgen action within a masculinization programming window (MPW; e15.5–e18.5 in rats) is important in the origin of male reproductive ...

Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1

Journal Article
Hutchison, G. R., Scott, H. M., Walker, M., McKinnell, C., Ferrara, D., Mahood, I. K., & Sharpe, R. M. (2008)
Sertoli Cell Development and Function in an Animal Model of Testicular Dysgenesis Syndrome1. Biology of Reproduction, 78(2), 352-360. https://doi.org/10.1095/biolreprod.107.064006
Pregnancy exposure to di(n-butyl) phthalate (DBP) in rats induces a testicular dysgenesislike syndrome (TDS) in male offspring. Earlier studies suggested altered Sertoli cell ...

Indoor CO2 and Thermal Conditions in Twenty Scottish Primary School Classrooms with Different Ventilation Systems during the COVID-19 Pandemic

Journal Article
Bain-Reguis, N., Smith, A., Hollins-Martin, C., & Currie, J. (2022)
Indoor CO2 and Thermal Conditions in Twenty Scottish Primary School Classrooms with Different Ventilation Systems during the COVID-19 Pandemic. Pollutants, 2(2), 180-204. https://doi.org/10.3390/pollutants2020014
Healthy indoor environments influence the comfort, health and wellbeing of the occupants. Monitoring the indoor temperature, relative humidity and CO2 levels in primary school...

Response of soil bacterial community composition and its associated geochemical parameters to rapid short-term cyclic groundwater-level oscillations: soil column experiments

Journal Article
Xia, X., Cheng, L., Zhu, Y., Liu, Y., Wang, K., Ding, A., …Zuo, L. (2020)
Response of soil bacterial community composition and its associated geochemical parameters to rapid short-term cyclic groundwater-level oscillations: soil column experiments. Vadose Zone Journal, 19(1), https://doi.org/10.1002/vzj2.20011
Groundwater-level oscillations change geochemical conditions, carbon cycling processes and bacterial community composition, and these changes may vary vertically with depth in...

In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome

Conference Proceeding
Girardi, G., Fraser, J., Bertolaccini, M. L., Lennen, R., Vontell, R., & Hutchison, G. (2014)
In vivo in uterus non-invasive methods to predict placental insufficiency and adverse pregnancy outcomes in antiphospholipid syndrome. https://doi.org/10.1016/j.placenta.2014.06.184
Objectives: To use MRI-based methods to non invasively detect placental insufficiency and predict fetal outcomes in obstetric antiphospholipid syndrome (APS) Methods and resul...

Socio-environmental Health. Exploring risk and resource spaces within urban environments. An interdisciplinary enquiry.

Presentation / Conference
Carnegie, E., Reid, A., Deakin, M., & Inglis, G. (2018, September)
Socio-environmental Health. Exploring risk and resource spaces within urban environments. An interdisciplinary enquiry. Paper presented at Space and Poverty (Salzburg Conference in Interdisciplinary Poverty Research
Regenerative spaces (good for health, environment and the planet) are essential for human flourishing. Findings from previous research suggest an association between spatial p...
7 results

Do iron-oxide nanoparticles contribute to Parkinsons Disease pathology?

2021 - 2022
Anthropogenic iron-oxide nanoparticles (IONPs) detected in ultrafine particulate matter caused by traffic and industrial emissions have increased substantially over time, constituting one of the most ...
Funder: RS Macdonald Charitable Trust | Value: £1,500

EXPOSURE OF RESPIRATORY NURSES TO SECOND-HAND SMOKE DURING PATIENT VISITS IN THE COMMUNITY

2024 - 2024
Although there has been a smoking ban across the UK for more than 15 years making it illegal to smoke in many workplaces there are still some circumstances where workers are being exposed to second-ha...
Funder: Association of Respiratory Nurse Specialists | Value: £8,077

Development of an innovative grid-scale energy storage to push UK and China renewables

2018 - 2024
Wind and solar energy holds a lot of promise when it comes to replace the conventional energy sources such as fossil fuels and coal. However, there is one problem: How do we store solar and wind energ...
Funder: ENU Development Trust | Value: £25,819

Quantifying metal bioaccumulation in Nephrops norvegicus larvae exposed to cadmium and pile-driving noise

2019 - 2020
Quantifying metal bioaccumulation in Nephrops norvegicus larvae exposed to cadmium and pile-driving noise - Understanding the impacts and mechanisms of multiple stressors on marine life is fraught wit...
Funder: Marine Alliance for Science & Technology for Scotland (Hosted by St Andrew's University) | Value: £950

Biomaterial Risk Management

2017 - 2022
Development of a reliable methodology for better risk management of engineered biomaterials in Advanced Therapy Medicinal Products and/or Medical Devices. BIORIMA stands for Biomaterial Risk Manageme...
Funder: European Commission | Value: £158,070

Pollution Exposure and Cardiovascular Health

2018 - 2019
The project aims to ascertain pollution exposure on Edinburgh main roads and greener routes, and also determine the health effects of active commuting via these routes
Funder: Carnegie Trust for the Universities of Scotland | Value: £4,550

Nanomaterials and wastewater treatment

2015 - 2016
In an attempt to better understand the impact of nanomaterials on waste water treatment, the University will undertake a purposeful environmental hazard assessment, whereby the focus will be to assess...
Funder: Centre for Environment Fisheries & Aquaculture Science | Value: £18,992

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